THE RESPONSE OF ISOLATED RABBIT ATRIA TO ACONITINE
نویسندگان
چکیده
منابع مشابه
Effects of magnesium on isolated rabbit atria.
The cardiac effects of magnesium were studied on 40 spontaneously beating rabbit atria at 37 degrees C. Magnesium administered in doses of 30, 60, 120 and 240 mmol elicited dose dependent negative inotropic and chronotropic responses. Larger doses above 240 mmol caused complete atrial arrest. Further it was observed that propranolol with magnesium became more effective in blocking the positive ...
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It has been reported that some of H1 receptor antagonists have important effects on cardiovascular system. Terfenadine as a non-sedative H1 receptor antagonist has an arrhythmogenic activity. In this study we have shown the effects of four antihistamine drugs: terfenadine, loratadine, clemastine and diphenhydramine, on the rate and contractions of isolated rat atria. Terfenadine (1-10 µM) cause...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology and Chemotherapy
سال: 1960
ISSN: 0366-0826
DOI: 10.1111/j.1476-5381.1960.tb01271.x